心肌酶谱联合超敏肌钙蛋白Ⅰ检测在冠心病诊断中的研究价值

The Research Value of Myocardial Zymogram Combined with High Sensitive Troponin Ⅰ in the Diagnosis of Coronary Heart Disease

目的:分析超敏心肌肌钙蛋白Ⅰ(hs-cTnI)联合心肌酶谱在冠心病诊断中的应用价值。方法:抽取某院78例冠心病患者纳入研究,作为观察组,均行心肌酶谱检测、心肌酶谱联合hs-cTnI检测,观察两种方法的检测准确率;同期抽取健康体检者78例作为对照组,观察两组心肌酶谱检测情况对比。结果:心肌酶谱联合hs-cTnI检查的准确率是56.41%(44/78),心肌酶谱检查准确率是19.23%(15/78),两组差异存在统计学意义(P<0.05);观察组的谷草转氨酶(AST)、肌酸激酶(CK)、肌酸激酶同工酶(CK-MB)、乳酸脱氢酶(LDH)、羟丁酸脱氢酶(HBDH)等心肌酶检测结果均比对照组高(P<0.05)。结论:hs-cTnI联合心肌酶谱在冠心病诊断中的应用价值显著,准确率高,值得推广。

Objective: To analyze the value of high sensitive troponin Ⅰ combined with myocardial zymogram in the diagnosis of coronary heart disease. Methods: 78 patients with coronary heart disease in a hospital were selected for the study as the observation group. Myocardial zymogram detection, myocardial zymogram combined with high-sensitivity troponin I detection were performed to observe the detection accuracy of the two methods. Meanwhile, 78 healthy people were selected as the control group to observe the comparison of myocardial zymogram detection between the two groups. Results: The accuracy rate of myocardial zymogram combined with HS cTnI was 56.41%(44/78);The accuracy rate of myocardial zymogram was 19.23%(15/78)(P<0.05). The results of myocardial enzymes such as aspartate aminotransferase(AST), creatine kinase(CK), creatine kinase isoenzyme(CK-MB), lactate dehydrogenase(LDH), hydroxybutyrate dehydrogenase(HBDH) and so on in the observation group were higher than those in the control group(P<0.05). Conclusion: The application of high sensitive troponin I combined with myocardial zymogram in the diagnosis of coronary heart disease is of great value, with high accuracy,which is worthy of promotion.