琥珀酸亚铁治疗妊娠合并缺铁性贫血的疗效与安全性分析

Efficacy and Safety of Ferrous Succinate in the Treatment of Iron Deficiency Anemia in Pregnancy

目的:探讨琥珀酸亚铁治疗妊娠合并缺铁性贫血的疗效与安全性。方法:从2017年5月~2019年2月时间段选取90例妊娠合并缺铁性贫血的患者,采用投掷硬币的方法将患者进行分组,分为对照组和观察组各45例,其中采用硫酸亚铁治疗并纳入对照组,另外采用琥珀酸亚铁治疗并纳入观察组,对比两组疗效及安全性。结果:不同方式治疗后,观察组患者97.8%的治疗有效率与对照组80.0%的治疗有效率比较,提升显著(P<0.05);不同方式治疗后,观察组不良反应率4.4%,与对照组24.4%的不良反应率比较,明显减少(P<0.05)。结论:针对妊娠合并缺铁性贫血患者,采用琥珀酸亚铁能取得良好的治疗效果,且不良反应少,安全有效,为临床治疗此类疾病提供重要的参考价值。

Objective:To investigate the efficacy and safety of ferrous succinate in the treatment of iron deficiency anemia in pregnancy.Methods:90 pregnant women with iron deficiency anemia from May 2017 to February 2019 were selected and divided equally by coin throwing.Among them,45 patients were treated with ferrous sulfate and included in the control group,and the other 45 patients were treated with ferrous succinate and included in the observation group.The efficacy and safety of the two groups were compared.Results:The effective rate in the observation group was 97.8%,which was significantly higher than that in the control group(80%,P<0.05).After treatment,the incidence of adverse reactions in the observation group was 4.4%,which was significantly lower than that in the control group(24.4%,P<0.05).Conclusion:For pregnant women with iron deficiency anemia,the use of ferrous succinate can achieve good results,with fewer adverse reactions,which is safe and effective,and provides an important reference value for clinical treatment of such diseases.