慢性肝病相关肌少症的影像学进展

Imaging progresses in evaluation of sarcopenia associated with chronic liver disease

肌少症是一组以骨骼肌质量减少、功能减退为主要特征的临床综合征,也是慢性肝病的并发症之一。影像学检查不仅能够反映肌肉结构和成分的变化,还可以定量评估肌肉的横截面积、体积以及肌肉内脂肪含量,是评估肌少症肌肉质量的重要工具。就双能X线吸收测定(DXA)、超声、CT、外周定量CT(pQCT)及MRI在慢性肝病肌少症中的临床应用及研究进展予以综述。

Sarcopenia is a group of clinical syndromes characterized by skeletal muscle mass reduction and dysfunction.It is also one of the complications of chronic liver disease.Imaging examination can not only reflect the changes of muscle structure and composition,but also quantitatively evaluate the cross-sectional area,volume,and muscle fat content,which is an important evaluation tool in the evaluation of muscle quality in sarcopenia.The clinical applications and research progresses of dual energy X-ray absorptiometry(DXA),ultrasound,CT,peripheral bone quantitative CT(pQCT),and MRI in patients with chronic liver disease sarcopenia were reviewed.