血清胱抑素C水平对妊娠期高血压疾病发生及妊娠结局的研究

Study on serum cystatin level in the occurrence of pregnancy-induced hypertension and pregnancy outcome.

目的探讨血清胱抑素C水平对妊娠妇女妊娠期高血压疾病的发生及妊娠结局的影响。方法采用回顾性方法选取2016年1月-2018年6月在昆明市妇幼保健院产科入院分娩的产妇为观察对象,按孕妇产前血清胱抑素C水平四分位数数值进行分组:分为A、B、C、D四组,比较血清胱抑素C水平四分位分组间母亲人口统计学、妊娠期高血压疾病发病率以及妊娠结局的差异。结果随血清胱抑素C水平的增加,妊娠期高血压疾病的发生率明显增加,妊娠期不良结局增加。

Objective To investigate the effect of serum cystatin levels on pregnancy outcomes of pregnant women with hypertension during pregnancy.Methods The retrospective method was used to select the women who were delivered in the obstetrics department of Kunming Maternity and Child Health Hospital from January 2016 to June 2018 as observation objects,and were grouped according to the quartile value of serum prenatal serum cystatin levels:Differences in maternal demographics,the incidence of hypertension during pregnancy,and pregnancy outcomes were compared between the four quartiles of serum cystatin levels in groups A,B,C,and D.Results With the increase of serum cystatin levels,the incidence of maternal hypertension during pregnancy increased significantly,and adverse pregnancy outcomes increased.