摘要
目的:探讨品行障碍(CD)少年及具有反社会人格(AP)成人注意保持的事件相关电位(ERP)特点。方法:对24例CD少年(CD组)和22例AP囚犯(AP组)进行注意保持的ERP检测,采用关联性负变(CNV)经典范式,分析刺激后500~1000 ms,1000~1500 ms和1500~2000 ms时段的CNV波幅,并与23名正常对照者(NC组)比较。结果:ERP结果显示,CNV波幅在500~1000 ms时段CD组[(-4.853±0.561)μV]和NC组[(-5.482±0.435)μV]比较差异无统计学意义,均明显高于AP组[(-3.446±0.486)μV](P均<0.05);1000~1500 ms及1500~2000 ms时段CD组[(-2.950±0.439)μV、(-0.645±0.695)μV]及AP组[(-2.857±0.347)μV、(-2.129±0.626)μV]显著低于NC组[(-4.813±0.358)μV、(2.251±0.647)μV](P均<0.01)。结论:CD少年注意知觉正常,但保持能力受损;AP囚犯注意保持能力缺乏;这可能与他们行为冲动和无计划相关。
Objective:To explore the electrophysiological characteristics of sustained attention on contingent negative variation in conduct disorder(CD)and antisocial personality(AP).Method:The 24 CD delinquents(CD group)and 22 prisoners with AP(AP group)were selected in current study by recording the event-related potentials in classic contingent negative variation(CNV)paradigm.The amplitude of CNV components of 500-1000 ms,1000-1500 ms and 1500-2000 ms in different progress were analyzed and compared with normal controls(NC group,n=23).Results:In 500-1000 ms average amplitude of CNV,the results showed that there was no significant difference in the amplitude of the CNV of CD group[(-4.853±0.561)μV]and that of NC group[(-5.482±0.435)μV],the amplitudes of the two groups were significantly higher than that of AP group[(-3.446±0.486)μV](all P<0.05).In 1000-1500 ms and 1500-2000 ms average amplitude of CNV,the amplitudes of the CNV in the CD group[(-2.950±0.439)μV,(-0.645±0.695)μV]and AP group[(-2.857±0.347)μV,(-2.129±0.626)μV]were significantly lower than those in the NC group[(-4.813±0.358)μV,(2.251±0.647)μV](all P<0.01).Conclusion:Process of sustained attention is impaired in CD delinquents,as AP prisoners has sustained attention absence,which may be associated with behavioral impulsivity and takin action without plan.
作者
关慕桢
黄微
廖扬
王亚培
刘旭峰
GUAN Mu-zhen;HUANG Wei;LIAO Yang;WANG Ya-pei;LIU Xu-feng(Deptement of Mental Health,Xi'an Medical University,Xi'an 710021,China)
出处
《临床精神医学杂志》
2021年第1期38-41,共4页
Journal of Clinical Psychiatry
基金
“十三五”全军后勤科研计划重点项目(BWS16J012)
西安医学院博士启动项目(2016D0C11)。
关键词
品行障碍
反社会人格
事件相关电位
关联性负变
conduct disorder
antisocial personality
event related potentials
contingent negative variation