生物学标志物对急性胰腺炎严重程度早期预测价值的研究进展

Advances in Research on Early Predictive Value of Biomarkers for Severity of Acute Pancreatitis

急性胰腺炎(AP)是常见的消化系统疾病,起病急,死亡率高,现有评分系统和生化指标对AP严重程度的早期预测具有复杂、滞后的特点。随着研究地深入,涌现出部分新的生化指标,如未成熟粒细胞百分比、红细胞体积分布宽度等,能及时有效地评估AP严重程度。本文就预测AP严重程度的生物学标志物的研究进展作一综述。

Acute pancreatitis(AP)is a commonly seen disease of digestive system and with the characteristics of acute onset and high mortality.The existing scoring systems and biochemical indices for early prediction of AP severity are complicated and lagging in time.With the deepening of research,the emergence of new biomarkers,such as immature granulocyte percentage,red blood cell distribution width,can timely and effectively assess the severity of AP.This article reviewed the progress of research on biomarkers for predicting the severity of AP.