北京地区全血献血者铁蛋白调查分析

Ferritin in whole blood donors:an investigation in Beijing

目的对北京地区全血献血者铁蛋白检测,分析与铁蛋白低值异常相关的影响因素,为全血献血者科学补铁提供依据。方法以2018年3~6月北京地区27 071名全血献血者为研究对象,进行铁蛋白检测。使用Logistics回归分析影响铁蛋白低值异常的献血者相关信息,确定最容易出现铁蛋白低值异常的全血献血者类型。结果北京地区全血献血者铁蛋白低值异常率为8.54%(2 311/27 071),献血者性别、是否为重复献血者和1年内献血次数,对铁蛋白低值异常有影响;年龄对铁蛋白低值率无显著影响。其中性别和1年内献血次数的影响最大,OR值分别为8.258(CI7.463~9.137)和2.148(CI1.856~2.485)。结论通过大规模人群调查,尽管现有献血策略下北京地区全血献血者铁储存状况优于其他国家,但应关注重复献血者铁蛋白低值状况。

Objective To detect the ferritin of whole blood donors in Beijing, and to analyze the influencing factors related to low level of ferritin, so as to provide scientific basis for iron supplementation of blood donors.Methods Ferritin was detected among 27 071 blood donors in Beijing area from March to June 2018. Related information of blood donors with low ferritin level was analyzed using Logistic regression analysis to determine the type of blood donors most likely to present low ferritin level. Results The rate of low ferritin value in whole blood donors in Beijing was 8.54%. The abnormal low ferritin was affected by gender, repeat donation behavior and the number of blood donations within one year, and not by age.The gender and the number of blood donations within one year presented great impact, with OR value at 8.258(CI7.463~9.137)and 2.148(CI1.856~2.485), respectively. Conclusion The iron storage status of whole blood donors in Beijing area under the current blood policy is better than that in other developed countries,revealed by a large-scale population survey,yet more attention should be paid to the ferritin status of repeat blood donors.