药用植物miRNA的研究进展

Research Progress of miRNA in Medicinal Plants

微小RNA(miRNA)是一类长约22个核苷酸的小分子单链RNA,可以在转录后水平调控基因表达,对人体的生长、发育、生理和病理过程具有重要的调控作用。有研究发现,中药的植物miRNA可以被稳定吸收进入体内,而发挥其特异性的药理作用。中药miRNA的研究极大地提高了现代药理研究对中药有效成分的认知水平,也为疾病治疗提供了新的途径,更为中药研究提供了一种新的研究思路与方法。

miRNA is a kind of small single stranded RNA with about 22 nucleotides,which can regulate gene expression at the post transcription level and plays an important role in human growth,development,physiology and pathology.It has been found that plant miRNA of traditional Chinese medicine(TCM)can be stably absorbed into the body to play its specific pharmacological role.The research on miRNA of TCM has greatly improved the cognitive level of modern pharmacological research on the effective components of TCM,and also provides a new way of treatment for diseases,as well as a new research idea and method for TCM research.