摘要
烟酰胺单核苷酸(NMN)作为生物体内烟酰胺腺嘌呤二核苷酸(NAD+)补救合成途径中的关键前体,能够一定程度上延缓衰老与治疗由于衰老引起的老年退行性疾病、2型糖尿病等。本文综述了NAD+的主要活性及其生物体内的生物合成方法,以及其前体NMN的最新的化学合成方法。
Nicotinamide mononucleotide(NMN) is a key precursor of nicotinamide adenine dinucleotide(NAD+)salvage pathway, which can delay aging, treat senile degenerative diseases and type 2 diabetes that caused by aging. In this paper, the main activities of NAD+ and its biosynthesis methods, as well as the latest chemical synthesis methods of its precursor NMN were reviewed.
作者
李旺
郭文彬
王晓季
Li Wang;Guo Wenbin;Wang Xiaoji(School of Life Science,Jiangxi Science and Technology Normal University,Nanchang 330013,Jiangxi,P.R.China;College of Chemical Engineering and Engergy Technology,Dongguan University of Technology,Dongguan 523830,Guangdong,P.R.China)
出处
《江西科技师范大学学报》
2020年第6期112-115,共4页
Journal of Jiangxi Science & Technology Normal University
基金
国家自然科学基金项目(21562020)。
