28例重症颅内静脉窦血栓患者抗凝治疗与联合血管内治疗预后分析

Prognosis analysis of anticoagulant therapy combined with endovascular therapy in 28 patients with severe Cerebral venous sinus thrombosis

目的分析重症颅内静脉窦血栓(Cerebral Venous Sinus Thrombosis,CVST)患者二种治疗方法的短期预后,探讨重症CVST患者的最佳治疗方法。方法回顾分析2013年1月至2019年1月昆明市第一人民医院神经外科28例确诊为CVST重症患者,分为单纯抗凝治疗组与抗凝联合血管内治疗组,分析比较二组的短期预后。结果抗凝联合血管内治疗组的短期预后良好率优于单纯内科抗凝组,差异具有统计学意义(P<0.05)。结论对于重症CVST抗凝治疗效果差患者,可尝试介入治疗,能有效改善患者短期预后。

Objective To analyze the short-term prognosis of two treatment methods for severe Cerebral venous sinus thrombosis(Cerebral Venous Sinus Thrombosis,CVST)and to explore the best treatment for severe CVST patients.Methods From January 2013 to January 2019,28 patients with severe cvst were diagnosed by neurosurgery in the first people’s hospital of Kunming.They were divided into two groups:simple internal anticoagulant therapy,anticoagulation and combined endovascular treatment.Results Anticoagulant combined with intravascular treatment group has a better short-term prognosis than that of medical anticoagulant group alone,the difference is statistically significant(P<0.05).Conclusions For patients with severe CVST,interventional therapy can be tried to improve the short-term prognosis.