老年支气管哮喘采用川芎平喘合剂治疗效果及对肺功能指标影响

Effect of Chuanxiong Pingchuan Mixture on senile bronchial asthma on pulmonary function index

目的探讨将川芎平喘合剂应用于老年支气管哮喘患者对其肺功能及临床效果产生的重要影响。方法随机抽取90例,均为齐河县人民医院在2019年1月~2019年12月期间诊治的老年支气管哮喘患者,应用随机数字表抽取法划分为对照组(n=45,布地奈德常规治疗)与观察组(n=45,川芎平喘合剂联合常规治疗),记录并分析两组患者的中医症候积分、肺功能指标及IL-6、TNF-α指标。结果观察组患者的各项症状积分同比对照组患者明显更低(P<0.05);观察组患者的FEV1、PEF指标明显高于治疗前及对照组患者(P<0.05);观察组患者的IL-6、TNF-α指标明显低于治疗前及对照组患者(P<0.05)。结论将川芎平喘合剂应用于老年支气管哮喘患者,其临床症状明显改善,炎性反应得到有效抑制,肺功能指标明显提升,整体治疗效果显著,值得临床应用。

Objective To investigate the effect of Chuanxiong Pingchuan mixture on lung function and clinical effect in elderly patients with bronchial asthma.Methods 90 cases of senile bronchial asthma treated by Qihe County People's Hospital during january 2019~december 2019 were randomLy selected and divided into control group(n=45,budesonide routine treatment)and observation group(n=45,chuanxiong pingchuan mixture combined with routine treatment).TCM symptom score,pulmonary function index and IL-6、TNF-αindex were recorded and analyzed in the two groups.Results The symptom scores of the patients in the observation group were significantly lower than those in the control group(P<0.05);the FEV1、PEF indexes in the observation group were significantly higher than those in the control group(P<0.05);the IL-6、TNF-αindexes in the observation group were significantly lower than those in the control group(P<0.05),and all the data differences were statistically significant.Conclusion Using Chuanxiong Pingchuan mixture in elderly patients with bronchial asthma,the clinical symptoms are obviously improved,the inflammatory response is effectively suppressed,the pulmonary function index is significantly improved,and the overall treatment effect is remarkable,which is worthy of clinical adoption.