大疱性类天疱疮伴发皮肤链格孢病1例

A case of bullous pemphigoid complicated with cutaneous alternariosis

患者,男,70岁。11个月前曾于外院诊断“大疱性类天疱疮”,长期口服“甲泼尼龙和环孢素”治疗。双侧前臂、双手背多发暗红色结节、溃疡半个月余。皮肤溃疡坏死物真菌镜检及培养证实为链格孢菌,经伏立康唑治疗皮损基本痊愈。

A male patient of seventy was diagnosed as bullous pemphigoid 11 months ago in another hospital and then treated with“methylprednisolone and cyclosporine”for a long time.There were multiple dark red nodules and ulcers on both of his forearms and hands for more than half a month.It was confirmed as Alternaria by fungal microscopic examination and culture of skin ulcer necrosis.Finally,the lesions basically disappeared after voriconazole treatment.