动态心电图HRV与伴高血压的隐匿型冠心病患者血压的相关性

Correlation between HRV detected by DCG and blood pressure in patients with latent coronary heart disease complicated hypertension

目的:探讨伴高血压的隐匿型冠心病(EH+LCHD)患者动态心电图(DCG)的心率变异性(HRV)与血压的相关性。方法:选择120例EH+LCHD患者和100例不伴高血压的LCHD患者,分别记为EH+LCHD组和单纯LCHD组。对比两组血压、DCG的HRV指标,分析EH+LCHD患者血压与HRV的相关性。结果:与单纯LCHD组比较,EH+LCHD组SBP[(121.86±10.03)mmHg比(165.32±11.26)mmHg]、DBP[(80.45±7.12)mmHg比(105.47±9.88)mmHg]、TI[(2871.52±312.65)mg 2/Hz比(3029.45±418.57)mg 2/Hz]和LF[(471.45±51.09)mg 2/Hz比(516.87±59.86)mg 2/Hz]均显著升高,HF[(278.62±40.68)mg 2/Hz比(259.60±42.54)mg 2/Hz]、SDNN[(103.98±11.25)ms比(89.74±10.17)ms]、SDANN[(96.67±9.18)ms比(79.46±7.85)ms]、rMSSD[(32.47±5.56)ms比(24.46±5.42)ms]、PNN50[(12.45±1.63)%比(8.37±1.33)%]和SDNNI[(48.77±5.69)比(38.55±5.12)]均显著降低,P均<0.01。Pearson相关分析显示,EH+LCHD患者SBP、DBP与TI、LF呈显著正相关(r=0.609~0.688,P<0.05或<0.01),与HF、SDNN、SDANN、rMSSD、PNN50和SDNNI呈显著负相关(r=-0.876~-0.601,P<0.05或<0.01)。结论:EH+LCHD患者HRV变化较单纯LCHD者更为严重,且SBP、DBP与TI、LF均呈显著正相关,与HF、SDNN、SDANN、RMSSD、PNN50、SDNN I均呈显著负相关。

Objective:To explore correlation between heart rate variability(HRV)detected by dynamic electrocardiogram(DCG)and blood pressure in patients with latent coronary heart disease complicated essential hypertension(LCHD+EH).Methods:A total of 120 EH+LCHD patients(EH+LCHD)and 100 LCHD patients without EH(pure LCHD group)were enrolled.Blood pressure and HRV indexes were compared between two groups.Correlation between blood pressure and HRV indexes were analyzed in EH+LCHD group.Results:Compared with pure LCHD group,there were significant rise in levels of SBP[(121.86±10.03)mmHg vs.(165.32±11.26)mmHg],DBP[(80.45±7.12)mmHg vs.(105.47±9.88)mmHg],TI[(2871.52±312.65)mg 2/Hz vs.(3029.45±418.57)mg 2/Hz]and LF[(471.45±51.09)mg 2/Hz vs.(516.87±59.86)mg 2/Hz],and significant reductions in HF[(278.62±40.68)mg 2/Hz vs.(259.60±42.54)mg 2/Hz],SDNN[(103.98±11.25)ms vs.(89.74±10.17)ms],SDANN[(96.67±9.18)ms vs.(79.46±7.85)ms],rMSSD[(32.47±5.56)ms vs.(24.46±5.42)ms],PNN50[(12.45±1.63)%vs.(8.37±1.33)%]and SDNNI[(48.77±5.69)vs.(38.55±5.12)]in EH+LCHD group,P<0.01 all.Pearson correlation analysis indicated that SBP and DBP were significant positively correlated with TI and LF(r=0.609~0.688,P<0.05 or<0.01),and significant inversely correlated with HF,SDNN,SDANN,rMSSD,PNN50 and SDNNI(r=-0.876~-0.601,P<0.05 or<0.01)in EH+LCHD patients.Conclusion:HRV changes in EH+LCHD patients is even more severe than those of pure LCHD patients.SBP and DBP are significant positively correlated with TI and LF,and significant inversely correlated with HF,SDNN,SDANN,rMSSD,PNN50 and SDNNI.