运动对老年T2DM患者心功能的影响

Influence of exercise on cardiac function in aged patients with T2DM

以舒张功能障碍为主的心功能障碍是老年2型糖尿病(T2DM)患者的主要并发症之一,患者的生活质量及预后会受到严重影响。运动干预可控制T2DM患者血糖,缓解心肌损伤,改善心功能,提高心肺耐力。本文就老年T2DM患者心脏结构及功能的损伤特点、运动干预改善心功能的相关机制及如何制订安全可行的个体化运动方案做一综述,以期为防治T2DM及改善老年T2DM患者心功能、减少并发症的发生提供新思路。

Cardiac dysfunction,mainly diastolic dysfunction,is one of the main complications in aged patients with type 2 diabetes mellitus(T2DM),and the quality of life and prognosis of patients will be seriously affected.Exercise intervention can control blood glucose,relieve myocardial injury,improve cardiac function and cardiorespiratory endurance in aged T2DM patients.The present article made a review on the characteristics of cardiac structure and function injury,related mechanisms of exercise intervention to improve cardiac function,and how to formulate a safe and feasible individualized exercise program in aged T2DM patients,aiming at providing new thinking for prevention and treatment of T2DM,improving cardiac function and reducing complications in aged T2DM patients.