围术期保温对老年手术患者炎性因子的影响

Effect of Perioperative Heat Preservation on Inflammatory Factors in Elderly Patients Undergoing Surgery

目的:探讨围术期保温对老年手术患者炎性因子的影响。方法:选取2018年1月至2018年12月至我院就诊的60例老年手术患者为研究对象,采用随机数字表分法将患者分为对照组、实验组两组,每组30人。对照组进行常规手术,实验组采用综合性保温措施。分别记录两组者麻醉前、后和术后鼻咽温度;麻醉前、术后IL-1、IL-6、TNF-α水平。结果:两组患者麻醉前、术后24h、48h、72h、120h时血清中IL-6、TNF-α、IL-1的水平显著上升,对照组患者的炎症因子水平明显高于实验组(P<0.05)。实验组麻醉前及麻醉后30、60、90、120min和术后鼻咽温度显著高于对照组(P<0.05)。结论:围术期保温术中保温有利于减少老年手术患者术中低体温的发生,降低术后免疫抑制程度,促进切口愈合。

Objective:To investigate the effect of perioperative heat preservation on inflammatory factors in elderly patients undergoing surgery.Methods:60 cases of elderly surgical patients from January 2018 to December 2018 in our hospital were selected as the research objects.The patients were randomly divided into control group and experimental group with 30 people in each group.The control group was given routine operation,and the experimental group was given comprehensive heat preservation measures.The nasopharynx temperature,the levels of IL-1,IL-6 and TNF-αbefore and after anesthesia were recorded.Results:The levels of IL-6,TNF-αand IL-1 in serum of the two groups were significantly increased before anesthesia and at 24 h,48 h,72 h and 120 h after operation,and the levels of inflammatory factors in the control group were significantly higher than those in the experimental group(P<0.05).The temperature of nasopharynx in experimental group was significantly higher than that in control group(P<0.05).Conclusion:Perioperative and intraoperative heat preservation can reduce the incidence of hypothermia,reduce the degree of postoperative immunosuppression,and promote wound healing.