免疫学检验联合检测在类风湿关节炎诊断中的临床价值

Analyze the clinical application of combined immunological test in the diagnosis of rheumatoid arthritis

目的:探讨免疫学检验联合检测在类风湿关节炎临床诊断中的价值。方法:选择2019年3月—2020年3月收治的非类风湿关节炎患者37例设为A组,选择同期收治的类风湿关节炎患者37例设为B组,两组均开展免疫学检验联合检测,总结分析两组临床检验结果。结果:B组患者的类风湿因子(RF)、抗角蛋白抗体(AKA)以及抗环瓜氨酸多肽抗体(抗CCP)阳性检出率均高于A组,差异有统计学意义(P<0.05);B组的IgG水平明显高于A组,补体C3与补体C4低于A组,两组比较差异均有统计学意义(P<0.05)。结论:免疫学检验联合检测用于类风湿关节炎的临床诊断,可有效提高类风湿关节炎疾病诊断的准确性。

Objective:To study the clinical value of combined detection using immunological tests in the clinical diagnosis of rheumatoid arthritis.Methods:The study was taken from March 2019 to March 2020,37 patients with non-rheumatoid arthritis received by hospital were selected as group A,and 37 patients with rheumatoid arthritis admitted during the same period were selected as group B.All the patients were conducted joint immunological tests,and analyzed the clinical test results of the two groups of patients after the study.Results:The test results showed that the positive detection rates of rheumatoid factor(RF),antikeratin antibody(AKA)and anti-cyclic peptide containing citrulline(anti-CCP)in group B were significantly higher than those in group A(P<0.05),the IgG levels in group B were significantly higher than those in group A,while complement the levels of C3 and C4 were significantly lower than those in group A(P<0.05).Conclusion:The combined detection of immunological test for clinical diagnosis of rheumatoid arthritis is ideal,which can effectively improve the accuracy of rheumatoid arthritis disease diagnosis.