透穴针刺法联合中药治疗恶性肿瘤放化疗后顽固性呃逆的临床观察

Clinical observation of point-through-point acupuncture combined with traditional Chinese medicine in the treatment of intractable hiccup after radiotherapy and chemotherapy for malignant tumor

目的观察透穴针刺法联合中药治疗恶性肿瘤患者放化疗后顽固性呃逆的临床效果。方法选取2018年5月-2019年9月北京市朝阳区三环肿瘤医院收治的恶性肿瘤放化疗后顽固性呃逆并中医辨证属寒热错杂型患者60例,按随机数字表法分为对照组(30例)和治疗组(30例)。对照组采用黄连汤加减治疗,治疗组采用针刺攒竹透鱼腰、内关透外关、足三里透阴陵泉联合黄连汤加减治疗。7 d为1个疗程,随访1周,观察两组治疗后临床疗效、起效时间以及随访1周复发率。结果治疗组治疗后总有效率明显高于对照组,差异有统计学意义(P<0.05)。治疗组平均起效时间短于对照组,差异有统计学意义(P<0.05)。治疗组随访1周复发率低于对照组,差异有统计学意义(P<0.05)。结论透穴针刺法联合中药治疗能有效改善肿瘤患者放化疗后属寒热错杂型顽固性呃逆的症状,起效时间短,复发率低。

Objective To investigate clinical effect of point-through-point acupuncture combined with traditional Chinese medicine in the treatment of intractable hiccup after radiotherapy and chemotherapy in patients with malignant tumor.Methods Sixty patients with intractable hiccup after radiotherapy and chemotherapy and traditional Chinese medicine syndrome differentiation belongs to the syndrome of intermingled heat and cold from May 2018 to September 2019 admitted to Sanhuan Cancer Hospital of Chaoyang District of Beijing City were selected.They were divided into control group(30 cases)and treatment group(30 cases)according to random number table method.Control group was treated with modified Huanglian Decoction.Treatment group was treated with acupuncturing cuánzhúthrough yúyāo,nèiguān through wàiguān,zúsānlǐthrough yīnlíngquán combined with modified Huanglian Decoction.Seven days as a course of treatment,followed up for one week.Clinical efficacy,onset time and relapse rate of followed up for one week between two groups after treatment were observed.Results Total effective rate of treatment group after treatment was higher than that of control group,the difference was statistically significant(P<0.05).The average onset time of treatment group was shorter than that of control group,the difference was statistically significant(P<0.05).The relapse rate of treatment group was lower than that of control group after one week follow-up,the difference was statistically significant(P<0.05).Conclusion Point-through-point acupuncture combined with traditional Chinese medicine can effectively improve the intractable hiccup with syndrome of intermingled heat and cold after radiotherapy and chemotherapy in patients with malignant tumor,with rapid onset of action and low replase rate.