经皮肾镜碎石术致尿源性脓毒血症的危险因素分析及早期预警研究

Risk Factors Analysis and Early Warning Study of Urogenic Sepsis Induced by Percutaneous Nephrolithotripsy

目的:探讨经皮肾镜碎石术致尿源性脓毒血症的危险因素分析及早期预警研究。方法:根据我院收治的时间在2016年1月截止在2020年3月治疗的尿源性脓毒血症患者200例作为观察对象,所有患者均实行经皮肾镜碎石术,治疗后对患者危险因素进行评估,比较患者的单因素分析和多因素分析。结果:单因素结果表明:经皮肾镜碎石术后导致尿源性脓毒血症与性别、年龄、糖尿病、结石大小、泌尿系感染、手术时间(min)、肾积水程度、术前抗菌药物应用相关,差异具有统计学意义(P<0.05);多因素Logistic分析结果表明:术后尿源性脓毒血症患者与年龄、性别、术中冲洗液的用量、是否使用抗菌药物、尿常规、尿培养、结石部位、通道大小、高血压有关,差异具有统计学意义(P<0.05)。结论:经皮肾镜碎石术致尿源性脓毒血症患者的危险因素进行分析,导致尿源性脓毒血症的因素较多,对于早期的相关因素进行治疗和加以控制,可以有效防止危险因素的发展,并且能够为患者的预后提供良好的条件,值得推广应用。

Objective:to investigate the risk factors and early warning of urogenic sepsis induced by percutaneous nephrolithotripsy.Methods:200 patients with urogenic sepsis treated in our hospital from January 2016 to March 2020 were taken as the observation objects.All patients underwent percutaneous nephrolithotripsy.Risk factors of the patients were evaluated after treatment,and univariate analysis and multivariate analysis were compared.Results:univariate results showed that urogenic sepsis after percutaneous nephrolithotripsy was correlated with gender,age,diabetes,calculi size,urinary tract infection,operative time(min),degree of hydronephrosis,and preoperative use of antimicrobial agents,with statistically significant differences(P<0.05).The results of multivariate Logistic analysis showed that patients with postoperative urogenic sepsis were correlated with age,gender,amount of intraoperative flushing fluid,use of antibiotics,urine routine,urine culture,stone site,channel size,and hypertension,with statistically significant differences(P<0.05).Conclusion:percutaneous nephroscope lithotripsy to urine source sex to analyze the risk factors in patients with sepsis,and lead to urinary source sex factors of sepsis is more,the related factors for early treatment and control,can effectively prevent the development of the risk factors,and can provide good conditions for the prognosis of patients,is worthy of popularization and application.