加速康复外科在老年早期非小细胞肺癌病人诊疗中的作用

Effect of enhanced recovery after surgery in the treatment of elderly patients with early non-small cell lung cancer

目的探讨加速康复外科(ERAS)在老年早期非小细胞肺癌病人中的应用效果。方法选取2018年6月至2019年5月在江苏省肿瘤医院胸外科采取胸腔镜肺叶切除术治疗的老年早期非小细胞肺癌病人248例。根据病人是否采取ERAS分为A组(采取ERAS)99例和B组(未采取ERAS)149例。观察2组病人的术后并发症(包括肺不张、胸腔积液、肺炎以及房颤)发生情况以及90 d死亡率。结果B组病人术后胸腔积液的发生率显著高于A组(P=0.045),其余并发症发生率差异无统计学意义。随访期间,2组均无死亡病例。结论遵循ERAS治疗的老年早期非小细胞肺癌病人能够获得更好的临床预后。

Objective To evaluate the effect of enhanced recovery after surgery(ERAS)in the elderly patients with early non-small cell lung cancer.Methods A total of 248 patients undergoing thoracoscopic pulmonary lobectomy for early non-small cell lung cancer from June 2018 to May 2019 in the Department of Thoracic Surgery of Jiangsu Cancer Hospital were selected.All the patients were divided into group A(99 cases receiving ERAS)and group B(149 cases without ERAS).The postoperative complications,including atelectasis,pleural effusion,pneumonia,atrial fibrillation and 90-day mortality were observed and compared between the two groups.Results The incidence rate of postoperative pleural effusion in group B was significantly higher than that in group A(P=0.045).During the follow-up,there were no deaths.There were no significant differences in other postoperative complications between the two groups.Conclusions Elderly patients with early non-small cell lung cancer undergoing ERAS have significantly greater prognosis.