基于中医瘀血理论探讨骨质疏松症中医发病机制认识及治疗进展

Discussion on the pathogenesis and treatment progress of osteoporosis based on the blood stasis theory in traditional Chinese medicine

随着我国社会人口老龄化日渐加剧,骨质疏松症(osteoporosis,OP)患病率亦显著增加,已成为我国三大老年慢性疾病之一。高发病率、严重并发症及昂贵的医疗费用等使其成为全球关注的公共健康问题。近年来以中医理论为指导的相关研究不断深入,显示出中医药治疗OP的独特优势。既往研究大多以“肾主骨生髓”理论进行研究,瘀血理论作为中医学基本理论之一,越来越多的研究表明其对OP防治具有独特的优势。本文将从血管内皮因子、红细胞相关指标、微循环状态及活血化瘀法临床疗效等阐明瘀血理论与OP发病的相关性方面进行综述,旨在为OP的进一步实验研究及临床辨证治疗提供依据。

With the aging of Chinese population,the prevalence of osteoporosis(OP)has increased significantly,and it has become one of the three major chronic diseases of the elderly in China.High incidence,serious complications and high medical costs have made it a public health problem of global concern.In recent years,the related researches guided by the theory of Traditional Chinese Medicine have been deepened continuously,showing the unique advantages of Traditional Chinese Medicine in the treatment of OP.Previous studies mostly studies the theory of kidney advocate bone marrow,blood stasis theory as the basic theory of TCM,More and more studies have shown that it has unique advantages for OP control.This article will review the relationship between vascular endothelial factor,red blood cell related indicators,microcirculation status and the clinical efficacy of the method of promoting blood circulation and removing blood stasis to clarify the relationship between blood stasis theory and the onsetof OP.It aims to provide a basis for further experimental research and clinical treatment of OP.