耐甲氧西林金黄色葡萄球菌的菌株分布和耐药性

Distribution and Drug Resistance of Methicillin-resistant Staphylococcus Aureus

目的针对耐甲氧西林金黄色葡萄球菌(MRSA)的菌株分布和耐药性进行分析研究。方法方便选取该院2018年8月—2019年7月分离得到的MRSA菌株样本79例作为研究对象,统计其分布情况,对菌株样本进行药敏试验,分析菌株的耐药性。结果痰液中检出的MRSA所占比例最高(56.96%),其次是分泌物(20.25%),再次是脓液(10.13%);MRSA科室分布为重症医学科和儿科最多(18.99%),其次是针灸康复科(11.39%)、骨科和呼吸内科(10.13%);药敏试验结果显示,MRSA耐药性从高到低的药物顺序是青霉素(100.00%)、利奈唑烷(56.96%)、红霉素(43.04%)、左氧氟沙星(36.71%)等。结论MRSA菌株于医院中多个科室均有分布,而且对多类抗生素耐药性较强,临床中需要对其加强关注,尽量避免感染。

Objective To analyze the distribution and drug resistance of methicillin-resistant Staphylococcus aureus(MRSA)strains.Methods A total of 79 samples of MRSA strains isolated in the hospital from August 2018 to July 2019 were selected as the research objects,and their distribution was counted.The strain samples were tested for drug sensitivity and the drug resistance of the strains was analyzed.Results The proportion of MRSA detected in sputum was the highest(56.96%),followed by secretions(20.25%),followed by pus(10.13%);MRSA departments were the most in intensive care medicine and pediatrics(18.99%),followed by Acupuncture and Rehabilitation(11.39%),Orthopedics and Respiratory Medicine(10.13%);the results of the drug sensitivity test showed that the drug resistance of MRSA from high to low is penicillin(100.00%),linezolid(56.96%),erythromycin(43.04%),levofloxacin(36.71%),etc.Conclusion MRSA strains are distributed in multiple departments in hospitals,and they are highly resistant to many types of antibiotics.It is necessary to pay more attention to them in clinical practice to avoid infection as much as possible.