周围神经趋化性再生研究新进展

Advances in chemotactic regeneration of peripheral nerve

周围神经损伤后修复及功能重建一直是临床治疗的难题。现从周围神经趋化性再生的概念,感觉与运动神经元自身差异、远侧端神经、施万细胞、成纤维细胞以及轴突导向因子等方面阐述了目前周围神经趋化性再生的研究进展,为将来开发更好的工程化神经组织,促进神经功能良好的恢复提供基础知识。

After peripheral nerve injury,the repair and functional reconstruction is always a difficult problem in clinical treatment.In this paper,the concept of chemotactic regeneration of peripheral nerve,the differences between sensory and motor neurons,the distal end of the nerve,Schwann cells,fibroblasts and axon guidance factors were reviewed,which will provide fundamental knowledge for developing better engineered nerve tissue and promoting the recovery of neural function in the future.