门冬胰岛素30结合二甲双胍治疗老年初诊2型糖尿病疗效观察

Observation on the Efficacy of Insulin Aspart 30 Combined with Metformin in the Treatment of Newly Diagnosed Type 2 Diabetes in the Elderly

目的探究门冬胰岛素30与二甲双胍联合治疗老年初诊2型糖尿病的效果。方法选取2017年7月—2019年6月该院收治的初诊2型糖尿病老年患者170例作为该次试验的研究对象,将其随机分为研究组与对照组,每组85例。给予对照组门冬胰岛素30治疗,给予研究组门冬胰岛素30与二甲双胍联合治疗。比较两组患者的治疗效果。结果研究组患者治疗后总有效率为96.47%,对照组为84.71%,差异有统计学意义(P<0.05);治疗后研究组患者各血糖指标下降明显,差异有统计学意义(P<0.05)。治疗后对照组患者产生不良反应率为3.53%,研究组为4.71%,差异无统计学意义(P>0.05)。结论使用门冬胰岛素30与二甲双胍联合治疗老年初诊2型糖尿病的降糖效果明显,可以考虑将此方法应用于此类患者的临床治疗。

Objective To explore the effect of insulin aspart 30 combined with metformin in the treatment of type 2 diabetes in the elderly.Methods 170 elderly patients with newly diagnosed type 2 diabetes who were admitted to the hospital from July 2017 to June 2019 were selected as the research objects of this trial,and they were randomly divided into the study group and the control group,each with its own 85 cases.The control group was given insulin aspart 30 treatment,and the study group was given insulin aspart 30 combined with metformin.The clinical effects of the two groups of patients after a period of treatment were compared.Results After treatment,the total effective rate of patients in the study group was 96.47%,and that in the control group was 84.71%,and the difference was statistically significant(P<0.05);after treatment,the blood glucose indexes of the patients in the study group decreased significantly,and the difference was statistically significant(P<0.05).After treatment,the probability of adverse reactions in the control group was 3.53%,and the study group consisted of 4.71%of patients,and the difference was not statistically significant(P>0.05).Conclusion The combination of insulin aspart 30 and metformin in the treatment of type 2 diabetes in the elderly has a significant effect on reducing blood glucose.This method can be considered for clinical treatment of such patients.