药学干预前后Ⅰ类切口手术预防使用抗菌药物的情况分析

Analysis of Prophylactic Use of Antibiotics in Type Ⅰ Incision Surgery before and after Pharmaceutical Intervention

目的:探讨药学干预前后Ⅰ类切口手术预防使用抗菌药物情况。方法:选择2015年1月-2018年1月本院收治的4 198例行Ⅰ类切口手术患者为研究对象,其中2015年1月-2016年12月为干预前(1 058例),2017年1月-2018年12月为干预后(3 140例)。采用回顾性分析方法对手术预防应用抗菌药物情况进行调查分析。比较药学干预前后抗菌药物用药情况。结果:干预后的不合理用药率明显低于干预前(P<0.05);干预后的头霉素、青霉素、三代头孢类及二代头孢类所占比例均低于干预前(P<0.05),一代头孢类高于干预前(P<0.05)。结论:通过将药学干预运用在Ⅰ类切口手术预防用抗菌药物中可以减少药物的不合理应用。

Objective:To investigate the prophylactic use of antibiotics in type Ⅰ incision surgery before and after pharmaceutical intervention.Method:A total of 4 198 patients with type Ⅰ incision surgery admitted to our hospital from January 2015 to January 2018 were selected as the research objects,The period from January 2015 to December 2016 was pre-intervention (1 058 cases) and the period from January 2017 to December 2018 was post-intervention (n=3 140 cases).Retrospective analysis was used to investigate and analyzed the application of antibiotics in operation prevention.Compared the situation of antibacterial drug use before and after pharmaceutical intervention.Result:The rate of irrational use of drug after the intervention was significantly lower than that before the intervention (P<0.05).The proportions of cephamycin,penicillin,third-generation and second-generation cephalospora after intervention were lower than those before intervention (P<0.05),the proportion of first generation cephalosporin after intervention was higher than that before intervention (P<0.05).Conclusion:The irrational use of drugs can be reduced by applying pharmaceutical intervention in prophylactic use of antibiotics in type Ⅰ incision surgery.