易损斑块的病理组织学特征和机制研究现状

Current research status on pathological characteristics and mechanisms of vulnerable plaque

易损斑块和(或)其结局斑块破裂继发腔内血栓是急性冠状动脉综合征的重要病生理基础,深入理解易损斑块的病理组织学特征及其机制是精准风险评估和治疗指导的前提。本文从病理组织学出发,综述了近年来易损斑块形成机制的相关研究。

Vulnerable plaque and intraluminal thrombosis subsequent to plaque rupture are the important pathophysiological mechanism of acute coronary syndrome.In-depth understanding of histopathological features and mechanism of vulnerable plaque contributes to risk assessment and clinical decision.Based on histopathology,this article reviews recent studies on the mechanism of vulnerable plaque formation.