不同年龄儿童肺炎支原体肺炎的临床特征及实验室指标

Clinical Characteristics and Laboratory Indexes of Mycoplasma Pneumoniae Pneumonia in Children of Different Ages

目的:分析不同年龄儿童肺炎支原体肺炎的临床特征及实验室指标。方法:根据年龄不同,将本院2017年9月-2018年9月收治的儿童肺炎支原体肺炎患儿分为A组(1~3岁)和B组(>3岁),各34例。患儿入院24 h内对其临床症状、血常规、免疫情况进行观察,确诊疾病。确诊后,两组均进行阿奇霉素+盐酸氨溴索治疗。比较两组临床症状、治疗效果、不良反应发生率。结果:A组发热发生率低于B组,A组咳痰、呼吸困难、气促、恶心呕吐发生率均高于B组,差异有统计学意义(P<0.05)。两组咳嗽发生率比较差异无统计学意义(P>0.05)。A组CRP、IgA水平低于B组,A组IgM水平高于B组,差异有统计学意义(P<0.05)。两组WBC、PLT、IgG水平比较差异无统计学意义(P>0.05)。两组治疗有效率、不良反应发生率比较差异无统计学意义(P>0.05)。结论:不同年龄儿童肺炎支原体肺炎患儿临床症状、CRP、IgA与IgM水平不同,临床应根据不同年龄患儿的特征,对疾病进行诊断。

Objective:To analyze the clinical characteristics and laboratory indexes of mycoplasma pneumoniae pneumonia in children of different ages.Method:Children with mycoplasma pneumoniae pneumonia admitted to our hospital from September 2017 to September 2018 were divided into the group A (1-3 years old) and the group B (>3 years old) according to their age,34 cases in each group.The clinical symptoms,blood routine,immune conditions were observed within 24 h of admission,confirmed the disease.After diagnosis,both groups were treated with Azithromycin + Ambroxol Hydrochloride.Result:The incidence of fever in the group A was lower than that in the group B,the incidence of expectoration,dyspnea,shortness of breath,nausea and vomiting in the group A were higher than that in the group B,the differences were statistically significant (P<0.05).There was no statistically significant difference in the incidence of cough between the two groups (P>0.05).The levels of CRP and IgA in the group A were lower than those in the group B,and the level of IgM in the group A was higher than that in the group B,with statistically significant differences (P<0.05).There were no significant differences in levels of WBC,PLT,IgG between the group A and the group B (P>0.05).There were no statistically significant differences in the effective rate of treatment and incidence of adverse reaction between the two groups (P>0.05).Conclusion:The clinical symptoms,CRP,IgA and IgM levels of children with mycoplasma pneumoniae pneumonia of different ages are different,clinical diagnosis should be made according to the characteristics of children of different ages.