复发性宫颈癌的治疗现状及进展

Current Status and Progress of Treatment of Recurrent Cervical Cancer

宫颈癌是女性生殖系统最常见的恶性肿瘤,尽管宫颈癌筛查不断普及,全球宫颈癌发病率较前下降,仍有约75%的宫颈癌患者在初始治疗后2年内复发。复发性宫颈癌严重影响患者的预后及生存率,但目前对于复发性宫颈癌尚无标准化治疗方案。随着肿瘤免疫疗法的出现、放射治疗方法的应用、化疗方案的不断完善以及手术方式的不断改进,复发性宫颈癌患者的治疗方案不断增加,但治疗过程中较高的并发症发生率仍不可忽视。因此,进一步完善复发性宫颈癌的治疗方法并提高患者的生存率仍是复发性宫颈癌治疗的重点和难点。本文就复发性宫颈癌的治疗现状及进展,从手术治疗、化学治疗、免疫治疗及放射治疗方面作一综述,旨在为复发性宫颈癌患者治疗方案的选择提供思路。

Cervical cancer is the most common malignant tumor in the female reproductive system.Despite the popularity of cervical cancer screening and the incidence of cervical cancer in the world is lower than before,about 75%of cervical cancer patients still relapse within two years after initial treatment.Recurrent cervical cancer seriously affects the prognosis and survival rate of patients,but there is no standardized treatment for recurrent cervical cancer.With the emergence of tumor immunotherapy,the application of radiotherapy,the continuous improvement of chemotherapy regimen,and the improvement of surgical methods,the treatment scheme of patients with recurrent cervical cancer is increasing,but the high incidence of complications during the treatment can not be ignored.Therefore,further improving the treatment of recurrent cervical cancer and improving the survival rate of patients is still a difficult point in the treatment of recurrent cervical cancer.This article reviews the current situation and progress of the treatment of recurrent cervical cancer,from the aspects of surgical treatments,chemotherapy,immunotherapy,and radiotherapy,aim to provide ideas for the choice of treatment options for patients with recurrent cervical cancer.