摘要
目的总结涎腺混合瘤与Warthin瘤的超声造影特征,分析二者的差异。方法回顾性分析我院经手术病理证实的17个涎腺混合瘤和16个Warthin瘤的超声造影特征。结果混合瘤超声造影表现以同进(76.5%)、向心性(64.7%)、不均匀性(76.5%)、低增强(70.6%)为主,增强后边界多清晰(88.2%),大部分可见增强环(94.1%),增强后肿块范围多不增大(88.2%)。Warthin瘤超声造影表现以快进(50.0%)、非向心性(87.5%)、不均匀性(62.5%)、高增强(56.3%)多见,大部分增强后边界清晰、可见增强环和增强后肿块范围不增大(均为93.8%)。涎腺混合瘤与Warthin瘤的增强方向和增强强度比较差异均有统计学意义(均P<0.05)。以非向心性增强诊断Warthin瘤的敏感性、特异性和准确率分别为87.5%、64.7%、75.8%;以高增强诊断Warthin瘤的敏感性、特异性和准确率分别为56.3%、100%、78.8%。以向心性增强诊断涎腺混合瘤的敏感性、特异性和准确率分别为64.7%、87.5%、75.8%;以低增强诊断涎腺混合瘤的敏感性、特异性和准确率分别为70.6%、87.5%、84.9%。结论涎腺混合瘤与Warthin瘤的超声造影表现具有一定的特征性,增强方向和增强强度指标有助于二者的鉴别诊断。
Objective To summarize the contrast-enhanced ultrasonic characteristics of pleomorphic adenomas and Warthin tumors of salivary gland.Methods Seventeen patients with pleomorphic adenomas and 16 patients with Warthin tumors underwent contrast-enhanced ultrasound examination and confirmed by surgical histopathology were retrospectively analyzed.Results The contrast-enhanced ultrasonic characteristics of pleomorphic adenomas were mainly synchronal(76.5%),centripetal(64.7%),inhomogeneity(76.5%)and hypo-enhancement(70.6%),with clear boundary after enhancement(88.2%),visible enhancement rim(94.1%),and no increase in the mass scope after enhancement(88.2%).The ultrasonic characteristics of Warthin tumors were fast fill-in(50.0%),non-centrality(87.5%),inhomogeneity(62.5%),and hyper-enhancement(56.3%).After enhancement,the boundary was clear,the enhancement rim was visible,and the mass scope was not increased(93.8%).There were statistically significant differences in the enhancement direction and enhancement intensity between pleomorphic adenomas and Warthin tumors(both P<0.05).The sensitivity,specificity and accuracy were 87.5%,64.7%,75.8%in the diagnosis of Warthin tumor by noncentric enhancement.The sensitivity,specificity and accuracy were 56.3%,100%,78.8%in the diagnosis of Warthin tumor by hyper-enhancement.The sensitivity,specificity and accuracy were 64.7%,87.5%,75.8%in the diagnosis of pleomorphic adenomas by centripetal enhancement.The sensitivity,specificity and accuracy were 70.6%,87.5%and 84.9%in the diagnosis of pleomorphic adenomas by hypo-enhancement.Conclusion The contrast-enhanced ultrasonic characteristics of pleomorphic adenomas and Warthin tumors have certain characteristics,and the enhancement direction and enhancement intensity parameters are helpful to differentially diagnose pleomorphic adenomas and Warthin tumors.
作者
韩明丽
史秋生
陈红燕
朱慧
杜联芳
王栋华
HAN Mingli;SHI Qiusheng;CHEN Hongyan;ZHU Hui;DU Lianfang;WANG Donghua(Department of Ultrasound,Minhang Hospital,Fudan University,Shanghai 201199,China)
出处
《临床超声医学杂志》
CSCD
2021年第2期135-138,共4页
Journal of Clinical Ultrasound in Medicine
基金
国家自然科学基金项目(81571677)
上海市闵行区自然科学研究课题(2019MHZ085)
上海市松江区科技攻关项目(18sjkjgg42)
上海市闵行区中心医院院级课题(2018MHLC07)。
关键词
超声检查
造影剂
混合瘤
WARTHIN瘤
涎腺
Ultrasonography
Contrast agent
Pleomorphic adenoma
Warthin tumor
Salivary gland