摘要
趋磁细菌是能沿磁场方向运动的特殊细菌,其趋磁机制尚存争议。该文通过建立趋磁细菌的运动学方程,仿真分析了反转磁场作用下趋磁细菌AMB-1的运动学特性。结合AMB-1动力学建模分析和实验结果表明,野生型菌株的运动特性与带有鞭毛的长椭球体基本吻合,而敲除类甲基受体趋化蛋白Amb0994后菌株对磁场反转的响应要比野生型菌株快,类似于没有鞭毛的长椭球体,这种行为差异可能是菌株鞭毛功能改变的结果;推测Amb0994可以通过控制鞭毛参与细菌对磁力矩变化的响应。这项研究有助于更深入地了解趋磁细菌的趋磁机制,并为探讨细菌鞭毛功能提供理论分析方法。
Magnetotactic bacteria are special bacteria that can move in the direction of a magnetic field,but their magnetotactic mechanism is still controversial.In this paper,by establishing the kinematic equation of magnetotactic bacteria,the kinematic characteristics of Magnetospirillum magneticum AMB-1 under the action of reversal magnetic field were analyzed.Combined with the AMB-1 dynamic modeling analysis and experimental results,it is shown that the motility characteristics of the wild-type strain are basically consistent with the prolate ellipsoid with flagella,the response of methyl-accepting chemotaxis like Amb0994 protein deleted mutant strain to abrupt reversals of magnetic field is faster than that of the wild-type strain,similar to an ellipsoid without flagella.This behavior difference may be caused by changes in flagella function.It is indicated that,Amb0994 can participate in the cellular response to magnetic torque changes by controlling flagella.This paper helps to understand the magnetotaxis mechanism in magnetotactic bacteria and provides a theoretical analysis method for exploring the function of bacterial flagella.
作者
陈海涛
陈林杰
石宏开
杜军渭
宋涛
Chen Haitao;Chen Linjie;Shi Hongkai;Du Junwei;Song Tao(Beijing Key Laboratory of Bioelectromagnetism,Institute of Electrical Engineering Chinese Academy of Sciences,Beijing 100190,China;University of Chinese Academy of Sciences,Beijing 100049,China;France-China International Laboratory of Evolution and Development of Magnetotactic Multicellular Organisms,Beijing 100190,China)
出处
《电工技术学报》
EI
CSCD
北大核心
2021年第4期717-723,共7页
Transactions of China Electrotechnical Society
基金
国家自然科学基金重点资助项目(51937011)。
关键词
磁场
趋磁细菌
动力学模型
鞭毛
Magnetic field
magnetotactic bacteria
dynamic model
flagella