眼底自发荧光检查在特发性黄斑裂孔诊断及视力预后判定中的应用

Applications of fundus autofluorescence on diagnosis and visual prognosis assessment of idiopathic macular hole

眼底自发荧光(fundus autofluorescence,FAF)作为一种操作简便、非侵入性的成像技术,可通过判断视网膜中脂褐质及黑色素的变化,以高/低荧光呈现视网膜功能状况。特发性黄斑裂孔(idiopathic macular hole,IMH)的FAF图像表现为黄斑裂孔高荧光区及孔周围的环形低荧光。术后裂孔完全闭合,高荧光区消失,否则表现为持续高荧光状态。FAF图像表现与相干光断层扫描图像及视力有相关性。(国际眼科纵览,2020,44:413-418)

Fundus autofluorescence(FAF)is a simple and non-invasive imaging modality.This technique based on the changes of lipofuscin and melanin within the retina,gives insight into metabolic condition of retina.The FAF imaging of idiopathic macular hole(IMH)shows hyperautofluorescence corresponding to the hole area and surrounding hypoautofluorescent ring.The hyperautofluorescence can disappear or reduce due to a successful macular hole closure,or can be persistent with an unclosed hole.FAF provides valuable information about diagnosis and follow-up of IMH,combined with OCT has a great role both in vision prognosis,understanding pathogenesis and anatomical and functional recovery.(Int Rev Ophthalmol,2020,44:413-418)