摘要
脊髓损伤患者存在罹患慢性肾脏疾病(CKD)的高风险,肾小球滤过率(GFR)是常用来检测CKD的一个重要指标。本文回顾现有的内源性和外源性GFR测量方法的优劣,并且重点分析GFR评估公式(eGFR)在脊髓损伤患者中应用产生的问题和面临的挑战。eGFR对脊髓损伤患者的适用性依然存在不足,有必要在脊髓损伤临床研究及应用中进行改良。
Patients with spinal cord injury are in high risk of chronic kidney disease(CKD).Glomerular filtration rate(GFR)is an important indicator commonly used to detect CKD.This paper reviewed the pros and cons of existing endogenous and exogenous GFR measurement,and focused on the problems and challenges for the application of the estimating glomerular filtration rate(eGFR)in patients with spinal cord injury.These research results indicated that the applicability of traditional eGFR to patients with spinal cord injury is still insufficient.It is necessary to modify eGFR in clinical research and application in spinal cord injury.
作者
谢杨
陈振波
杨吉刚
XIE Yang;CHEN Zhen-bo;YANG Ji-gang(Capital Medical University School of Rehabilitation Medicine,Beijing 100068,China;Medical Imaging Department,Beijing Bo'ai Hospital,China Rehabilitation Research Center,Beijing 100068,China;Nuclear Medicine Department,Beijing Friendship Hospital,Capital Medical University,Beijing 100050,China)
出处
《中国康复理论与实践》
CSCD
北大核心
2021年第2期145-149,共5页
Chinese Journal of Rehabilitation Theory and Practice
基金
国家自然科学基金项目(No.81971642)。
关键词
脊髓损伤
慢性肾脏疾病
肾小球滤过率
测量
评估公式
综述
spinal cord injury
chronic renal disease
glomerular filtration rate
measurement
evaluation formula
review
