摘要
目的探讨中药对肝损伤干预作用的分子生物学表达机制。方法分别从化学性肝损伤、免疫性肝损伤、酒精性肝损伤、药物性肝损伤及其他类肝损伤5个方面,回顾中药对肝损伤基因的干预作用。结果与结论中药对肝损伤基因具有良好的防护作用,相关药物应用前景广阔。
Objective To investigate the molecular biological expression mechanism of the intervention effects of traditional Chinese medicine on liver injury.Methods The intervention effects of traditional Chinese medicine on the liver injury genes were reviewed through evidence-based method from the following five aspects:chemical liver injury,immunity liver injury,alcohol liver injury,drug-induced liver injury and other liver injury.Results and Conclusion Traditional Chinese medicine has a good protective effect on liver injury genes,and the application prospect of related drugs is broad.
作者
李军民
高秉红
李平
LI Junmin;GAO Binghong;LI Ping(Lanzhou University Second Hospital,Lanzhou,Gansu,China 730030;Jumpcan Pharmaceutical Group Co.,Ltd.,Taixing,Jiangsu China 225400;Key Laboratory of Digestive System Tumors,Lanzhou,Gansu,China 730030)
出处
《中国药业》
CAS
2021年第4期96-96,I0001-I0005,共6页
China Pharmaceuticals
基金
甘肃省自然科学基金[145RJZA207]
兰州大学第二医院科研项目[ynbskyjj2015-2-17]
兰州大学第二医院院内中医药科研项目[YJzy2013-26]。
关键词
中药
肝损伤
基因
分子生物学
traditional Chinese medicine
liver injury
genes
molecular biology