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泛基因型直接抗病毒药物治疗慢性丙型肝炎肝硬化患者疗效及安全性分析 被引量：2

Pan-genotype direct antiviral drugs for treatment of patients with chronic hepatitis C and liver cirrhosis efficacy and safety analysis
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摘要 慢性丙型肝炎病毒(hepatitis C virus,HCV)感染是严重的全球公共卫生问题,据统计,在全球范围内大约有7100万例丙型肝炎感染者,我国约有1000万例HCV感染者[1-3]。慢性丙型肝炎是持续进展性疾病,如果不及时治疗,持续的慢性感染会导致肝纤维化,最终导致肝硬化,并增加与肝硬化相关的并发症的风险,尤其是失代偿期肝硬化和肝癌。目前已鉴定出HCV的6种主要基因型(genotype,GT)和67种亚型,其中GT-1型最常见(49.1%)[4]。
作者 张亚苹 王凤梅 Zhang Yaping;Wang Fengmei
机构地区 天津医科大学三中心临床学院 天津市第三中心医院消化肝病科
出处 《实用器官移植电子杂志》 2021年第1期70-74,I0002,共6页 Practical Journal of Organ Transplantation(Electronic Version)
关键词 慢性丙型肝炎 失代偿期肝硬化 全球公共卫生 丙型肝炎感染 泛基因 肝纤维化 及时治疗 慢性感染
分类号 R512.63 [医药卫生—内科学] R575.2 [医药卫生—消化系统]
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实用器官移植电子杂志
2021年 第1期

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