Lessons from Coronavirus Disease 2019 Infections in Children

The novel coronavirus disease 2019(COVID-19)in human caused by novel severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)is currently rampant across the world,causing an international concern for public health emergency.At the time of July,2020,about 8380000 confirmed cases and more than 450000 deaths have been reported worldwide.This is the third outbreak of severe coronavirus family after the Middle East respiratory syndrome(MERS)and severe acute respiratory syndrome(SARS).Young victims(<12 years)in clinical course and prognosis of pediatric COVID-19 appear symptomatically milder than do teenage and adult patients,and many children with asymptomatic infections or showing only mild symptoms may be transmitter as well.Thus,the children with COVID-19 infection deserve more attention.This review is cautiously designed to report the clinical characteristics and symptoms of three kinds of coronaviruses(SARS-CoV,MERS-CoV,and SARS-CoV-2)in children and to summarize some recommended tactics to reduce COVID-19 transmission and/or to attain improved prevention in children.