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丙泊酚与依托咪酯全麻诱导对老年手术患者血流动力学指标及苏醒质量影响的对比观察 被引量:9

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摘要 目的比较丙泊酚与依托咪酯全麻诱导对老年手术患者血流动力学指标及苏醒质量的影响。方法选取于南阳医学高等专科学校第一附属医院2018年4月至2019年2月择期行全麻手术的67例老年患者,依据盲抽法分为对照组(n=34)与观察组(n=33)。对照组予以丙泊酚行麻醉诱导,观察组予以依托咪酯行麻醉诱导,比较两组各时间点血流动力学指标[心率(HR)、平均动脉压(MAP)、血氧饱和度(SpO2)]及苏醒质量。结果观察组麻醉诱导前(T0)、麻醉诱导后插管前1 min(T1)、麻醉诱导后插管后1 min(T2)各时间点HR、MAP、SpO2对比,差异未见统计学意义(P>0.05)。对照组T0、T1、T2各时间点HR、MAP、SpO2比较,差异有统计学意义(P<0.05)。观察组T1、T2时HR、MAP、SpO2与对照组比较,差异有统计学意义(P<0.05)。观察组术后呼之睁眼时间、拔管时间、麻醉恢复室滞留时间均较对照组低,差异有统计学意义(P<0.05)。两组Steward苏醒评分比较,差异未见统计学意义(P>0.05)。结论相较丙泊酚,依托咪酯应用于老年手术患者全麻诱导期对患者HR、MAP、血SpO2指标影响较小,苏醒质量更高,利于临床推广应用。
出处 《临床医学》 CAS 2020年第12期55-57,共3页 Clinical Medicine
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