白虎加人参汤治疗重症肺部感染的效果

Effect of Baihu plus Ginseng Soup on treatment of severe pulmonary infection

目的探讨白虎加人参汤辅助治疗对重症肺部感染患者血清C-反应蛋白(C-reactive protein,CRP)、降钙素原(Procalcitonin,PCT)的影响及预后改变。方法选取2017年6月-2019年6月就诊于浙江省丽水第二人民医院的重症肺部感染患者100例,随机将其分为试验组与对照组,每组50例。对照组患者采取常规治疗方案,试验组患者在其基础上加中医药辅助治疗。评价两组患者的临床疗效;记录并比较两组患者的机械通气时间、临床症状改善时间、住院时间;比较两组患者治疗前后血清PCT及CRP水平。结果试验组的临床总有效率为90.00%,高于对照组的72.00%,差异有统计学意义(P<0.05);试验组患者的体温恢复时间、肺部啰音消失时间、血象恢复时间、机械通气时间、住院时间均短于对照组,差异均有统计学意义(P<0.05);治疗后,试验组患者的血清PCT及CRP水平低于对照组,差异有统计学意义(P<0.05)。结论在常规治疗方案上加用中医药辅助治疗重症肺部感染患者,可有效降低体内炎症水平,改善患者预后。

OBJECTIVE To explore the effect of Chinese medicine on the prognosis and serum levels of PCT and CRP in patients with severe pulmonary infection. METHODS From Jun. 2017 to Jun. 2019, 100 patients with severe pulmonary infection in Lishui Second People’s Hospital of Zhejiang Province were divided into the observation group(n=50) and control group(n=50). The patients in the control group were treated with conventional therapy, whereas the patients in the observation group were treated with traditional Chinese medicine. The clinical efficacy between two groups was evaluated;and the mechanical ventilation time, clinical symptoms improvement time and hospitalization time between the two groups were recorded;the serum PCT and CRP levels between the two groups before and after treatment were compared. RESULTS The total clinical effective rate in the observation group(90.00%) was significantly higher than that in the control group(72.00%). The mechanical ventilation time, lung rale disappearance time, body temperature recovery time, blood picture recovery time and hospitalization time in the observation group were significantly shorter than that in the control group(P<0.05). After the treatment, the levels of PCT and CRP in the observation group were significantly lower than that in the control group(P<0.05). CONCLUSION Assistant treatment of traditional Chinese medicine in patients with severe pulmonary infection can effectively reduce the level of inflammation and improve the prognosis of disease in patients.