基于《中华医典》的骨痹辨治规律及用药特点分析

Study on the Medication Laws and Prescriptions Rules of Heumatism from the Chinese Medical Classics Based on Date Mining Technology

目的:通过对中医古籍中骨痹文献的挖掘及研究,分析骨痹的辨治用药规律,为现代中医临床诊治骨痹提供指导。方法:提取《中华医典》中骨痹相关数据,建立骨痹诊治数据库,运用SPSS 21.0进行频数统计分析。结果:从171部古籍中纳入原文935条,收录方剂306首,药物599味(共8534次),数据分析得到核心药物10味、核心药对46对、核心药组42组、核心药团28项及聚类方7个。结论:挖掘分析骨痹的诊治规律和用药特点,既为中医治疗骨痹的规范化提供了理论依据,又为临床防治骨痹提供了新思路和新方法。

Objective:To provide guidance for the clinical diagnosis and treatment of heumatism by documents about medication features and differentiation treatment rules of heumatism from ancient books of Chinese medicine.Methods:In order to build a database for heumatism,files fromChinese Medical Classics were obtained,and SPSS 21.0was used to do frequency statistical analysis.Results:935sentences,306prescriptions and 599 medicines(8534times in total)were accepted from 171ancient books.10core drugs,46pairs of core drugs,42groups of core drugs,28teams of core drugs and 7clustering methods of core drugs were obtained from the statistical analysis.Conclusion:The medication features and analysis of differentiation treatment rules of heumatism not only provides theoretical bases for the standardization of Chinese medicine treatment of heumatism,but also provides new ideas and methods for the clinical treatment of heumatism.