不孕患者子宫输卵管超声造影术后自然妊娠情况分析

Analysis of spontaneous pregnancy after hysterosalpingo-contrast sonography in infertile women

目的:分析子宫输卵管超声造影(HyCoSy)术后不孕症患者的自然妊娠情况,探讨HyCoSy术后期待治疗的时间节点及适宜人群。方法:选取接受HyCoSy的不孕症患者1279例,随访6个月经周期,分析其术后自然妊娠情况及影响妊娠的相关因素。结果:HyCoSy术后6个月经周期内,304例患者获得宫内妊娠,累积妊娠率为23.77%(304/1279)。其中93.09%(283/304)患者在术后4个月经周期内妊娠。随着时间的推移,妊娠率逐渐下降。多因素分析显示,妊娠组和未孕组中的年龄、不孕病程、不孕类型、输卵管通畅程度、盆腔手术史及体重指数(BMI)比较,差异有统计学意义(P<0.05)。结论:子宫输卵管超声造影可在短期内提升不孕女性的自然妊娠率。

Objective:To investigate the impact of hysterosalpingo-contrast sonography(HyCoSy)on spontaneous pregnancy in infertilewomen and explore the period and suitable population of expectant treatment after HyCoSy.Methods:1,279 infertile patients who received HyCoSy were followed up for 6 menstrual cycles.Their situation of spontaneous pregnancy and the factors influencing pregnancy were analyzed.Results:A total of 304 patients got intrauterine normal pregnancy until 6 menstrual cycles after HyCoSy and the accumulative pregnant rate accounted for 23.77%(304/1279).Among them,93.09%(283/304)were pregnant within 4 menstrual cycles.Over time,the pregnancy rate gradually decreased.Multivariate analysis showed that there were significant differences in age,duration of infertility,type of infertility,patency of fallopian tubes,history of pelvic surgery and body mass index(BMI)between pregnant group and non-pregnant groups(P<0.05).Conclusion:HyCoSy improve the spontaneous pregnancy rate of women in a short period.