老年人群生活方式评分与血脂异常和高尿酸血症的关联研究

The Association of Lifestyle Score with Dyslipidemia and Hyperuricemia in the Elderly Population

目的研究老年人群生活方式评分与血脂异常、高尿酸血症的关联。方法以2016年武汉市某区参与体检的21390名老年人为研究对象,根据吸烟、饮酒、饮食、运动、体质指数、腰围情况计算其生活方式评分,采用Logistic回归和多元线性回归分别探究生活方式评分与血脂异常和高尿酸血症、血脂水平和尿酸水平的关系。结果与生活方式评分为0~1分的老年人相比,评分5~6分的老年人患血脂异常(OR=0.464,95%CI=0.398~0.541)和高尿酸血症(OR=0.550,95%CI=0.449~0.675)的风险显著降低,且甘油三酯水平(-0.292 mmol/L)和血清尿酸水平(-28.437μmol/L)显著降低、高密度脂蛋白胆固醇水平(0.179 mmol/L)显著升高。结论生活方式评分的增加(即健康生活方式因素的增加)可显著降低血脂异常和高尿酸血症风险。

Objective To investigate the association of lifestyles score with dyslipidemia and hyperuricemia in the elderly.Methods In 2016,21390 elderly people who participated in the physical examination in a district of Wuhan were included in the study.Their lifestyle scores were calculated based on status of smoking,drinking,diet,exercise,body mass index,and waist circumference.Logistic regression and multiple linear regression analysis were used to explore the relationship between lifestyle scores and dyslipidemia,hyperuricemia,blood lipid levels and uric acid le-vels.Results Compared with the elderly with a lifestyle score of 0 to 1,the elderly with a score of 5 to 6 had lower risk of dyslipidemia(OR=0.464,95%CI=0.398~0.541)and hyperuricemia(OR=0.550,95%CI=0.449~0.675).Their triglyceride level(-0.292 mmol/L)and serum uric acid level(-28.437μmol/L)significantly decreased,and the high-density lipoprotein cholesterol level(0.179 mmol/L)increased.Conclusion An increase in lifestyle scores(that is,an increase in healthy lifestyle factors)can significantly reduce the risk of dyslipidemia and hyperuricemia.