酒精性肝硬化患者营养风险及影响因素分析

Analysis of nutritional risk and influencing factors in patients with alcoholic liver cirrhosis

目的探讨酒精性肝硬化患者的营养风险及其相关影响因素,分析饮酒、营养风险与家庭关怀度的相关性。方法选取2018年12月至2019年6月该院门诊及住院收治的100例肝硬化患者为研究对象,其中酒精性肝硬化及非酒精性肝硬化各50例,采用营养风险筛查表(NRS2002)筛查两组营养风险状况,采用logistic回归法分析酒精性肝硬化患者营养风险的独立危险因素,采用Spearman相关性分析法分析饮酒、营养风险与酒精性肝硬化患者家庭关怀度的相关性。结果酒精性肝硬化组营养不良率(80.00%)明显高于非酒精性肝硬化组(56.00%,P<0.05)。性别、婚姻状况、日饮酒量、前清蛋白(PA)、血清清蛋白(ALB)和血红蛋白(Hb)及家庭关怀度指数测评表(PAGAR)评分为影响酒精性肝硬化患者营养风险的相关因素(P<0.05)。性别(男)、婚姻状况(非婚状态)、日饮酒量(>40 g)、ALB(低)、Hb(低)及PAGAR评分(<6分)为酒精性肝硬化患者营养风险的独立危险因素(P<0.05);Spearman相关性分析法结果显示,家庭关怀度与饮酒、营养风险均呈负相关性(P<0.05)。结论需对酒精性肝硬化患者采取个性化的健康指导,从而起到戒酒、改善营养状况和促进疾病康复的目的。

Objective To explore the nutritional risk and its related factors in patients with alcoholic cirrhosis,and analyze the correlation between drinking,nutritional risk and family care.Methods A total of 100 outpatients and inpatients with compensatory cirrhosis in hospital from December 2018 to June 2019 were selected,including 50 cases of alcoholic cirrhosis and 50 cases of nonalcoholic cirrhosis.NRS2002 was used to screen the nutritional risk of the two groups.logistic regression was used to analyze the independent risk factors of nutritional risk of alcoholic cirrhosis.Spearman correlation analysis was used to analyze the correlation between drinking,nutritional risk and family care of alcoholic cirrhosis.Results The malnutrition rate of 80.00%in the alcoholic cirrhosis group was significantly higher than that of 56.00%in the non-alcoholic cirrhosis group(P<0.05).Gender,marital status,daily alcohol consumption,prealbumin(PA),serum albumin(ALB),hemoglobin(Hb)and family care index evaluation form(PAGAR)scores were related factors(P<0.05).Gender(male),marital status(non marital status),daily alcohol consumption(>40 g),ALB(low),Hb(low)and PAGAR scores(<6 points)were independent risk factors that affect the nutritional risk of patients with alcoholic cirrhosis(P<0.05).The results of Spearman correlation analysis showed that family care was negatively correlated with drinking and nutrition risk(P<0.05).Conclusion Individualized health guidance was needed to be adopted for patients in clinical practice,so as to stop drinking,improve nutritional status and promote the purpose of disease recovery.