磁共振扩散加权成像指标在肝细胞癌微血管侵犯中的预测分析

Predictive analysis of DWI index in hepatocellular carcinoma microvessel invasion

目的分析磁共振扩散加权成像(Diffusion weighted imaging,DWI)表观扩散系数值(Apparent diffusion coefficient,ADC)与指数化表观扩散系数值(Exponential apparent diffusion coefficient,eADC)在肝细胞癌(Hepatocellular carcinoma,HCC)微血管侵犯(Microvascular invasion,MVI)中的预测价值。方法选择2018年2月至2020年2月本院收治的HCC患者70例,所有患者均于术前采用DWI扫描,术中取组织经病理诊断证实为HCC。记录临床病理诊断结果及ADC值、ADC值T/L、eADC值、eADC值T/L,并对DWI下相关指标预测HCC发生MVI的价值分析。结果经病理结果分析,HCC患者MVI阳性为19例,MVI阴性为51例。MVI阳性组的ADC值、ADC值T/L均低于MVI阴性组,eADC值T/L高于MVI阴性组,差异有统计学意义(P<0.05);ADC值T/L预测HCC患者MVI的曲线下面积(AUC)大于ADC值、eADC值T/L,敏感度最高,诊断价值较高。结论DWI下ADC值与HCC患者MVI具有一定的关系,ADC值T/L预测患者MVI的诊断价值较高。

Objective To analyze the predictive value of magnetic resonance diffusion weighted imaging(DWI)apparent diffusion coefficient value(ADC)and exponential apparent diffusion coefficient value(eADC)in hepatocellular carcinoma(HCC)microvascular invasion(MVI).Methods A total of 70 HCC patients admitted to our hospital from February 2018 to February 2020 were selected.All patients were scanned by DWI before operation,and tissues were taken for pathological diagnosis during operation,which was confirmed HCC.The clinicopathological diagnosis results,and the ADC value,ADC value T/L,eADC value,eADC value T/L were recorded,and the value of MVI occurrence of HCC predicted by relevant indicators under DWI were analyzed.Results According to the analysis of pathological results,there were 19 cases of MVI positive and 51 cases of MVI negative in HCC patients.The ADC value and ADC value T/L of the MVI positive group were lower than those of the MVI negative group,and the eADC value T/L was higher than that of the MVI negative group,the difference was statistically significant(P<0.05).The area under the curve(AUC)of ADC value T/L predicting HCC was greater than the ADC value and eADC value T/L,with the highest sensitivity and diagnostic value.Conclusion The ADC value under DWI has a certain relationship with the MVI of HCC patients.The diagnosis value of ADC value T/L predicting MVI is relatively higher.