苏州社区成人尿微量白蛋白/尿肌酐比值的调查分析

Investigation and analysis of the ratio of urine microalbumin/urinary creatinine in adults in Suzhou community

目的调查分析苏州社区人群成人尿微量白蛋白/尿肌酐比值(UACR)的分布以及异常率,为慢性病的防治提供理论基础。方法选取2017年7月—2020年1月,在苏州高新区横塘、浒关、阳山、镇湖、狮山、通安、东渚7个医联体社区建档的社区成人居民,共收集14350名。检测所有人的随机尿微量白蛋白、尿肌酐值,并计算UACR值。比较不同年龄组、不同性别UACR分布的差异,不同年龄组、不同年份人群UACR异常率的差异。结果不同年龄组人群UACR值比较,差异有统计学意义(P<0.05)。进一步两两比较,70~<80岁组、≥80岁组UACR值与其他年龄组比较,差异有统计学意义(P<0.05)。同年龄组女性UACR水平高于男性,差异有统计学意义(P<0.05)。不同性别各年龄组UACR值比较,差异有统计学意义(P<0.05)。不同年龄组UACR异常率比较,差异有统计学意义(P<0.05)。2017—2020年UACR异常率比较,差异有统计学意义(P<0.05)。结论UACR值的分布与性别和年龄都有密切关系,重点关注本地区50岁以下和70岁以上人群的疾病变化,同时关注每年数据变化,加强肾脏早期损害的筛查防治。

Objective To investigate and analyze the distribution and abnormal rate of urinary microalbumin/urinary creatinine ratio(UACR)among adults in Suzhou community provide a theoretical basis for the prevention and treatment of chronic diseases.Methods The community adult residents filed in seven medical consortium communities in Suzhou High-tech Zone,Hengtang,Hu’guan,Yangshan,Zhenhu,Shishan,Tongan,and Dongzhu were selected from July 2017 to January 2020,while 14350 cases were collected.All random urine microalbumin and urine creatinine values were detected,and the UACR value was calculated.The differences in the distribution of UACR in different age groups and genders,and the differences in the abnormal rates of UACR in different age groups and in different years were compared.Results Comparison of UACR values among different age groups showed statistically significant differences(P<0.05).Further pairwise comparisons,the UACR values of the 70 to 80 years old group and the≥80 years old group were compared with other age groups,and the differences were statistically significant(P<0.05).The UACR level of women in the same age group were higher than that of men,and the differences were statistically significant(P<0.05).Comparison of UACR values of different genders and age groups showed statistically significant differences(P<0.05).Compared with the abnormal rate of UACR in different age groups,and the differences were statistically significant(P<0.05).Compared with the abnormal rate of UACR from 2017 to 2020,and the differences were statistically significant(P<0.05).Conclusion The distribution of UACR values is closely related to gender and age.The focus is on disease changes in people under 50 and over 70 in the region.At the same time,attention is paid to changes in data every year to strengthen the screening and prevention of early kidney damage.