阿莫西林联合果胶铋治疗慢性萎缩性胃炎的效果分析

Analysis of the Effect of Amoxicillin Combined with Pectic Bismuth Treatment on Chronic Atrophic Gastritis

观察阿莫西林联合果胶铋治疗慢性萎缩性胃炎(CAG)的临床效果,分析药物的作用机制。选择50例CAG患者,分为常规组与试验组,每组各25例。常规组单用阿莫西林,试验组采用阿莫西林联合果胶铋,比较两组的治疗总有效率、治疗前后症状积分及不良反应发生情况。试验组的治疗总有效率为96.0%,显著高于常规组的72.0%(P<0.05)。治疗后,两组患者的症状积分均显著低于治疗前,试验组的症状积分显著低于常规组,差异有统计学意义(P<0.05)。不良反应发生率,常规组占12.0%,试验组占8.0%,差异无统计学意义(P>0.05)。推荐CAG患者采用阿莫西林联合果胶铋方案,能显著减轻患者的临床症状,优化疗效,用药安全性较高。

The research observes the clinical effect of amoxicillin combined pectic bismuth treatment on chronic atrophic gastritis(CAG),and analyzes the medicine function mechanism.50 CAG patients are divided into routine group and experimental group,with 25 patients in each group.Routine group receive amoxicillin,and experimental group receive amoxicillin combined with pectic bismuth treatment.Total curative effective rate,symptom score before and after treatment and adverse reaction occurrence situation of two groups are compared.Total curative effective rate of experimental group is 96.0%,which is significantly higher than 72.0%in routine group(P<0.05).After treatment,the symptom scores of two groups are significantly lower than before treatment,and the symptom scores of experimental group is significantly lower than routine group,with statistically significant difference(P<0.05).The adverse reaction occurrence rates of routine group and experimental group are 12.0%and 8.0%,with no statistically significant difference(P>0.05).Amoxicillin combined pectic bismuth treatment on chronic atrophic gastritis(CAG)patients can significantly reduce the clinical symptom,and optimize curative effect.The medication security is high.