摘要
目的:通过主成分分析和聚类分析评价不同厂家维C银翘片的质量。方法:采用HPLC法测定维C银翘片中绿原酸、牛蒡苷、维生素C、对乙酰氨基酚和马来酸氯苯那敏含量,基于测定结果进行主成分分析和聚类分析,评价不同厂家维C银翘片质量。结果:5个厂家维C银翘片有效成分含量均符合规定,但存在较大差异,主成分分析和聚类分析结果表明,同一厂家样品质量稳定。结论:主成分分析和聚类分析结果可为不同厂家维C银翘片的质量控制提供参考。
Objective The quality of Vitamin C Yinqiao Tablets from different manufacturers was evaluated using principal component analysis(PCA)and cluster analysis(CA).Method high performance liquid chromatography(HPLC)was used to determine the main components of Vitamin C Yinqiao Tablets from different manufacturers and perform cluster analysis.PCA and CA were conducted by using IBM SPSS 18.0 software to evaluate the quality of Vitamin C Yinqiao Tablets.Results The samples from different manufacturers met the requirements of China Phamacopoeia.And it was found that there were differences in the effective ingredient contents of Vitamin C Yinqiao Tablets.The results of PCA and CA showed that that the sample quality from the same manufacturer was uniform.Conclusions The results of CA and PCA can provide reference for quality control of Vitamin C Yinqiao tablet.
作者
崔新刚
王颖莹
CUI Xingang;WANG Yingying(Luoyang Maternal and Child Health Hospital,Luoyang 471023,China;Luoyang Food and Drug Inspection Institute,Luoyang 471023,China)
出处
《中国民族民间医药》
2021年第3期40-43,共4页
Chinese Journal of Ethnomedicine and Ethnopharmacy
关键词
HPLC
维C银翘片
有效成分
聚类分析
主成分分析
HPLC
Vitamin C Yinqiao Tablet
Bioactive Compounds
Hierarchical Cluster Analysis
Principal Component Analysis