128层螺旋CT结肠成像在结直肠癌诊断中的应用

Application of 128-slice spiral CT colonography in diagnosing colorectal cancer

目的探讨128层螺旋CT结肠成像(CTC)在结直肠癌诊断中的临床应用价值。方法选择82例疑似结直肠癌患者进行CTC和结肠镜检查,以结肠镜病理结果为标准,分析CTC诊断结直肠癌的灵敏度、特异度、阳性预测值、阴性预测值、定位、分型;其中16例手术的结直肠癌患者,以手术病理分期为标准,分析CTC在结直肠癌T分期中的准确度。结果以结肠镜病理结果为标准,CTC诊断结肠癌的灵敏度为100%,特异度90.91%,阳性预测值90.48%,阴性预测值100%,定位准确度100%,大体分型准确度为88.09%。以手术病理分期为标准,CTC结直肠癌T分期准确度为87.00%。结论 128层螺旋CTC在结直肠癌的定位、定性诊断及T分期上具有较高的准确度,可作为结直肠癌筛查的有效手段和术前常规检查。

Objective To explore the clinical value of 128-slice spiral CT colonography(CTC)in the diagnosis of colorectal cancer.Methods Totally 82 patients with suspected colorectal cancer who underwent CTC and colonoscopy were selected.The sensitivity,specificity,positive predictive value,negative predictive value,localization and classification of CTC in the diagnosis of colorectal cancer were analyzed according to the pathological results of colonoscopy.Taking the pathological staging as the gold standard,the accuracy of CTC diagnosis in T staging of colon cancer was analyzed in 16 patients with colorectal cancer who underwent surgery.Results The diagnostic sensitivity,specificity,positive predictive value,negative predictive value,positioning accuracy and general classification accuracy of CTC for diagnosing colorectal cancer were 100%,90.91%,90.48%,100%,100%,88.09%,respectively.Taking pathological staging during operation as the gold standard,the accuracy of CTC for diagnosing T staging of colorectal cancer was 87.00%.Conclusion 128-slice spiral CTC has high accuracy in the location,qualitative diagnosis and T staging of colorectal cancer.It can be used for colorectal cancer screening and routine examination before operation.