阿莫西林与替硝唑治疗急性肠胃炎的效果观察

Effect of Amoxicillin and Tinidazole on Acute Gastroenteritis

目的观察阿莫西林与替硝唑治疗急性肠胃炎的效果。方法以本院2018年4月—2019年4月收治的60例急性肠胃炎患者作为研究对象,借助双盲随机抽样法分为对照、试验组,每组列入30例,对照组给予阿莫西林治疗,试验组予以阿莫西林与替硝唑联合治疗,评定两组患者的临床效果、肠胃炎症状积分。结果治疗前,两组患者的肠胃炎症状积分无显著差异,P>0.05(t=0.0752,P=0.9403);治疗后,试验组相较于对照组患者的肠胃炎症状积分较低,P<0.05(t=14.5841,P=0.0000);试验组(96.67%)较对照组(76.67%)临床效果较高,P<0.05(χ^(2)=5.1923,P=0.0226)。结论急性肠胃炎患者予以阿莫西林与替硝唑联合治疗具有积极意义,值得临床研究。

Objective To observe the effect of amoxicillin and tinidazole on acute gastroenteritis.Methods Sixty patients with acute gastroenteritis admitted in our hospital from April 2018 to April 2019 were selected as the research objects.They were divided into control group and experimental group by double-blind random sampling method.30 cases in each group.The control group was treated with amoxicillin,and the experimental group was treated with amoxicillin and tinidazole.The clinical effect and symptom score of gastroenteritis were evaluated.Results Before treatment,there was no significant difference in gastrointestinal symptom scores between the two groups of patients,P>0.05(t=0.0752,P=0.9403).After treatment,the experimental group had lower gastrointestinal symptom scores than the control group.P<0.05(t=14.5841,P=0.0000);the experimental group(96.67%)had a higher clinical effect than the control group(76.67%),P<0.05(χ^(2)=5.1923,P=0.0226).Conclusion The combined treatment of amoxicillin and tinidazole in patients with acute gastroenteritis is of positive significance,which is worthy of clinical investigation.