β‑谷甾醇药理作用研究进展

Advances on pharmacology ofβ‑sitosterol

β‑谷甾醇是一种植物甾醇,不仅广泛存在于坚果、植物油、谷物中,也是多种中药植物的重要组成成分。β‑谷甾醇在人体内发挥多种有益的作用,目前备受医药及食品领域研究人员的关注,研究主要集中在β‑谷甾醇对多种疾病的治疗功效及相关医药产品的研发等方面。本文结合β‑谷甾醇的性质与结构,阐述其分离鉴定的研究现状,从抗菌、抗炎、抗氧化、抗动脉粥样硬化、降脂、抗脱发、抗抑郁、抗衰老、调节骨代谢等方面探讨其生理活性以及在各类临床疾病中的应用,为β‑谷甾醇的医药研发提供参考。

β‑sitosterol is a plant sterol,which is widely found in nuts,vegetable oils and grains.In addition,β‑sitosterol is also an important component of many traditional Chinese medicine plants.β‑sitosterol exerts beneficial effects in the human body,which has attracted the attention of researchers in the fields of medicine and food.The research mainly focuses on the therapeutic effect ofβ‑sitosterol on a variety of diseases and the development of related pharmaceutical products.Combined with the properties and structure ofβ‑sitosterol,this paper expounds the research status of its isolation and identification,and discusses its physiological activity and application in various clinical diseases from the aspects of antibacterial,anti‑inflammatory,antioxidant,anti‑atherosclerosis,lipid‑lowering,anti‑alopecia,antidepression,anti‑aging,and regulation of bone metabolism,so as to provide reference for the pharmaceutical research and development ofβ‑sitosterol.