探讨老年重症肺炎伴发呼吸衰竭采用无创呼吸机治疗的疗效

Exploration on the effect of non-invasive ventilator in the treatment of elderly patients with severe pneumonia and respiratory failure

目的:探讨采用无创呼吸机治疗老年重症肺炎合并呼吸衰竭的临床效果。方法:2017年4月-2020年5月收治老年重症肺炎合并呼吸衰竭患者62例,随机分为两组,各31例。试验组采用无创呼吸机治疗,对照组采用鼻导管吸氧法治疗,比较两组治疗效果。结果:试验组左室舒张末期内径(LVEDD)、呼吸频率(RR)及心率(HR)水平均低于对照组,左室射血分数(LVEF)水平高于对照组,差异有统计学意义(P<0.05);试验组白细胞介素-6(IL-6)、白细胞介素-1β(IL-1β)及炎性介质肿瘤坏死因子-α(TNF-α)水平均明显低于对照组,差异有统计学意义(P<0.05)。结论:无创呼吸机的有效运用,可使老年重症肺炎合并呼吸衰竭患者心功能及炎性反应获得有效改善以及缓解,实现有效预后。

Objective:To explore the clinical effect of non-invasive ventilator in the treatment of severe pneumonia with respiratory failure in elderly patients.Methods:From April 2017 to May 2020,62 cases of elderly patients with severe pneumonia and respiratory failure were enrolled,they were randomly divided into two groups with 31 cases in each group.The experimental group was treated with non-invasive ventilator.The control group was treated with nasal catheter oxygen inhalation.The therapeutic effects between the two groups was compared.Results:The levels of left ventricular end-diastolic diameter(LVEDD),respiratory rate(RR)and heart rate(HR)in the experimental group were lower than those in the control group,left ventricular ejection fraction(LVEF)level was higher than that of the control group,the differences were statistically significant(P<0.05).The levels of interleukin-6(IL-6),interleukin-1β(IL-1β)and tumor necrosis factor-α(TNF-α)in the experimental group were significantly lower than those in the control group,the differences were statistically significant(P<0.05).Conclusion:The effective use of non-invasive ventilator can effectively improve and alleviate the cardiac function and inflammatory response in elderly patients with severe pneumonia complicated with respiratory failure and it can achieve effective prognosis.