孟鲁司特钠联合舒利迭治疗支气管哮喘疗效观察

Observation on the curative effect of montelukast sodium combined with seretide in the treatment of bronchial asthma

目的:探讨孟鲁司特钠与舒利迭联合用药治疗支气管哮喘的临床效果。方法:2019年1月-2020年3月收治支气管哮喘患者110例,根据治疗用药不同分为两组,各55例。对照组单独应用孟鲁司特钠治疗,观察组联合应用孟鲁司特钠与舒利迭治疗,比较两组治疗总有效率、肺功能指标水平以及用药不良反应等。结果:观察组治疗总有效率明显优于对照组,差异有统计学意义(P<0.05)。两组治疗前肺功能各项指标水平比较,差异无统计学意义(P>0.05);两组治疗后肺功能各项指标水平均得到明显改善,且观察组改善情况明显优于对照组,差异有统计学意义(P<0.05)。观察组不良反应发生率略低于对照组,但差异无统计学意义(P>0.05)。结论:孟鲁司特钠与舒利迭联合用药治疗支气管哮喘,可有效改善患者肺功能,提升治疗效果,且不良反应少,安全性高,临床推广意义显著。

Objective:To investigate the clinical effect of montelukast sodium combined with seretide in the treatment of bronchial asthma.Methods:From January 2019 to March 2020,110 cases of patients with bronchial asthma were enrolled,they were divided into two groups according to different drugs,with 55 cases in each group.The control group was treated with montelukast sodium alone.The observation group was treated with montelukast sodium combined with seretide.The total effective rate of treatment,indicator levels of pulmonary function and adverse drug reactions between the two groups were compared.Results:The total effective rate of treatment in observation group was better than that in control group,the difference was statistically significant(P<0.05).The indicator levels of pulmonary function between the two groups before treatment was compared,the difference was not statistically significant(P>0.05).After treatment,the indicator levels of lung function of the two groups was improved obviously,the improvement of lung function in the observation group was obviously better than that in the control group,the difference was statistically significant(P<0.05).The incidence of adverse reactions in the observation group was slightly lower than that in the control group,the difference was not statistically significant(P>0.05).Conclusion:Montelukast sodium combined with seretide in the treatment of bronchial asthma can effectively improve the lung function and improve the therapeutic effect of the patients,the adverse reactions are less,the safety is high and the clinical significance is remarkable.