新型冠状病毒肺炎出院患者核酸复检阳性分析

Analysis of the positive for nucleic acid retesting in discharged COVID-19 patients

目的了解新型冠状病毒肺炎(简称新冠肺炎)治愈患者出院后14 d内核酸复检阳性率,分析复检阳性影响因素和传播风险,为有效管理出院患者提供依据。方法对86例出院患者的随访信息和核酸检测结果进行分析,计算出院后14 d内的核酸复检阳性率,分析性别、年龄、感染来源、临床严重程度、病程和住院时间等因素与复检阳性的统计学关联。结果 86例出院患者均无发热、乏力、干咳等新冠肺炎相关症状,8例(9.30%)患者核酸复检阳性;性别、年龄、感染来源、临床严重程度与出院后核酸复检阳性无统计学关联(P>0.05);病程和住院时间与核酸复检阳性有统计学关联(P<0.05);共追踪8例核酸复检阳性患者的密切接触者20人,未发现感染者。结论病程和住院时间为出院后核酸复检阳性的影响因素,建议出院患者进行14 d的隔离管理。

Objective To investigate the positive rate of severe acute respiratory syndrome coronavirus 2(SARS-CoV-2) nucleic acid retesting in cured COVID-19 patients within 14 days after discharge, to analyze the influencing factors for retesting positive and transmission risk of discharged COVID-19 patients, and to provide a basis for effectively manage the discharged patients. Methods The follow-up information and nucleic acid testing results of 86 discharged patients were analyzed. The positive rate of nucleic acid retesting within 14 days after discharge was calculated. The statistical correlations of factors such as gender, age, source of infection, clinical severity, course of disease and length of hospital stay with the positive rate of nucleic acid retesting were analyzed. Results No COVID-19-related systems like fever, weakness and dry cough were found in the 86 discharged patients, but 8(9.30%) patients were positive for nucleic acid retesting. There was no statistical association of gender, age, source of infection and clinical severity with the positive for nucleic acid retesting after discharge(P>0.05). The course of disease and length of hospital stay were statistically correlated with the positive for nucleic acid retesting after discharge(P<0.05). A total of 20 close contacts of 8 patients with positive nucleic acid retesting results were followed up, but no infection was found. Conclusions The course of disease and the length of hospital stay are factors influencing the positive for nucleic acid retesting in discharged patients. The results suggest that the discharged patients should be isolated for 14 days.